The 2008 North African Cup Winners Cup was the first edition of the competition created by the Federation of North African Football. ES Tunis were the champions, defeating JSM Béjaïa 2-1 over two legs.
|Algeria||JSM Béjaïa (Algerian Cup Winners 2007-08)|
|Libya||Khaleej Sirte (Libyan Cup Winners 2007-08)|
|Morocco||Maghreb Fez (Coupe du Trône Runners-Up 2007-08)1|
|Tunisia||ES Tunis (Tunisia Cup Winners 2007-08)|
2Al Zamalek withdrew.